SG can provide a whole suite of services to validate gene function in different cell signaling pathways. Proteins and antibodies are generated in-house to facilitate in vitro and in vivo target validations. Animal models can be established with IVIS (in vivo imaging system).

Gene network analysis is one of the most advanced biological technologies which enable us to better understand the mechanism of action of drugs and to identify novel drug targets and biomarkers.

Our company has long-term commitment and expertise in siRNA knockdown technology and bioinformatics analysis. Our gene networks are estimated from a large volume of microarray data (siRNA knocked down and drug treatment time course) including thousands of genes in the specific cells by using sophisticated bayesian network algorithms with super computer systems. While these networks provide information of the cell-type specific gene-gene relationships of several thousand gene pairs, these network analysis will identify specific target and pathways upon particular stimuli (e.g. drugs). This approach is a good supplement to existing biology research tools and should assist the research and development of safer and more effective drugs.