Shanghai Genomics (SG) can provide a whole suite of services to validate gene functions in different cell signaling pathways. Proteins and antibodies are generated in-house to facilitate in-vitro and in-vivo target validations. Animal models can be established with IVIS (in-vivo imaging system).

Gene network analysis is an advance biological technology that enables us to better understand drug mechanisms and to identify novel drug targets and biomarkers.

Shanghai Genomics has a long-term commitment and much expertise in siRNA knockdown technology and bioinformatics analysis. Our gene networks are derived from a large volume of micro-array data (siRNA knowck down and drug treatment time courses). Thousands of genes in specific cells have been established by using complex Bayesian network algorithms and super computer systems. While these networks provide information of the cell-type and specific gene-gene relationships between gene pairs; network analysis programs identify specific targets and pathways upon particular stimuli (e.g. Drugs). This approach is an excellent supplement to existing biological research tools and supports the research and development of safer and more effective drugs.