Shanghai Genomics (SG) has generated numerous stable cell lines for gene function studies, compound screenings, and IVIS systems.

Luc cell lines are bioluminescence producing cell lines used in conjunction with in-vivo imaging systems (IVIS). They offer unique opportunities to measure tumor growth and metastasis in a variety of models.

Services Include:

1)     Customized Luc Cell Line Generation

2)     11 Constructed Luc Cell Line Tumor Types for In-Vivo Animal Models

In-vivo bioluminescent imaging allows the non-invasive detection and quantification of orthotropic, metastatic, and spontaneous tumors. IVIS can also non-invasively detect micro metastases with high sensitivity, visualize metastases generated from primary tumors spontaneously and assess anti-cancer therapies over the course of treatment in-vivo. Luc cell lines can link luciferase expressions to signal transduction pathways, which is a key to the oncogenic process. These models offer the ability to track activation of factors that signal cell death, survival, or angiogenesis.